A MATLAB-based program for three-dimensional quantitative analysis of micronuclei reveals that neuroinflammation induces micronuclei formation in the brain

The micronucleus is known to be a biomarker for genomic instability, which is a hallmark of tumors and aging. Normally, micronuclei are produced by segregation errors and mechanical stresses arising from dividing or migrating cells, leading to activation of the innate immune response pathway. Althou...

Descripción completa

Detalles Bibliográficos
Autores principales: Yano, Sarasa, Akiyama, Kaito, Tsuchiya, Rio, Kubotani, Hikari, Chiba, Tomoki, Nagata, Takeshi, Tsuruta, Fuminori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443747/
https://www.ncbi.nlm.nih.gov/pubmed/34526560
http://dx.doi.org/10.1038/s41598-021-97640-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443747/
https://www.ncbi.nlm.nih.gov/pubmed/34526560
http://dx.doi.org/10.1038/s41598-021-97640-6

Ejemplares similares