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Concomitant and decoupled effects of cigarette smoke and SCAL1 upregulation on oncogenic phenotypes and ROS detoxification in lung adenocarcinoma cells

Lung cancer is the leading cause of cancer deaths worldwide, with smoking as its primary predisposing factor. Although carcinogens in cigarettes are known to cause oncogenic DNA alterations, analyses of patient cohorts revealed heterogeneous genetic aberrations with no clear driver mutations. The co...

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Detalles Bibliográficos
Autores principales: Cruz, Carmela Rieline V., Ferrer, Jose Lorenzo M., Garcia, Reynaldo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443756/
https://www.ncbi.nlm.nih.gov/pubmed/34526564
http://dx.doi.org/10.1038/s41598-021-97869-1