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Activation of β3-adrenoceptor increases the number of readily releasable glutamatergic vesicle via activating Ca(2+)/calmodulin/MLCK/myosin II pathway in the prefrontal cortex of juvenile rats
It is well known that β3-adrenoceptor (β3-AR) in many brain structures including prefrontal cortex (PFC) is involved in stress-related behavioral changes. SR58611A, a brain-penetrant β3-AR subtypes agonist, is revealed to exhibit anxiolytic- and antidepressant-like effects. Whereas activation of β3-...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443757/ https://www.ncbi.nlm.nih.gov/pubmed/34526598 http://dx.doi.org/10.1038/s41598-021-97769-4 |