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Structural characterization of KKT4, an unconventional microtubule-binding kinetochore protein

The kinetochore is the macromolecular machinery that drives chromosome segregation by interacting with spindle microtubules. Kinetoplastids (such as Trypanosoma brucei), a group of evolutionarily divergent eukaryotes, have a unique set of kinetochore proteins that lack any significant homology to ca...

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Detalles Bibliográficos
Autores principales: Ludzia, Patryk, Lowe, Edward D., Marcianò, Gabriele, Mohammed, Shabaz, Redfield, Christina, Akiyoshi, Bungo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443799/
https://www.ncbi.nlm.nih.gov/pubmed/33915106
http://dx.doi.org/10.1016/j.str.2021.04.004