An antibody-drug conjugate with intracellular drug release properties showing specific cytotoxicity against CD7-positive cells

Refractory T cell acute leukaemias that no longer respond to treatment would benefit from new modalities that target T cell-specific surface proteins. T cell associated surface proteins (the surfaceome) offer possible therapy targets to reduce tumour burden but also target the leukaemia-initiating c...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Jain, Arvind, Milhas, Sabine, Williamson, Daniel J., Mysliwy, Justyna, Lodge, Adam, Thirlway, Jenny, Al Nakeeb, Majid, Miller, Ami, Rabbitts, Terry H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443841/
https://www.ncbi.nlm.nih.gov/pubmed/34062328
http://dx.doi.org/10.1016/j.leukres.2021.106626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443841/
https://www.ncbi.nlm.nih.gov/pubmed/34062328
http://dx.doi.org/10.1016/j.leukres.2021.106626

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