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Influence of ascorbic acid and α-tocopherol on the autoxidation and in vitro antifungal activity of amphotericin B

BACKGROUND AND PURPOSE: Amphotericin B (AmB) is the standard treatment for systemic fungal infections; however, the formation of reactive oxygen species reduces the efficacy and stability of this molecule. The present study aimed to evaluate the effect of the combination of AmB with ascorbic acid an...

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Detalles Bibliográficos
Autores principales: Belhachemi, Mohammed Habib, Boucherit-Otmani, Zahia, Boucherit, Kebir, Belmir, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Medical Mycology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443877/
https://www.ncbi.nlm.nih.gov/pubmed/34553092
http://dx.doi.org/10.18502/cmm.7.1.6178