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Selectivity of the collagen-binding integrin inhibitors, TC-I-15 and obtustatin

Integrins are a family of 24 adhesion receptors which are both widely-expressed and important in many pathophysiological cellular processes, from embryonic development to cancer metastasis. Hence, integrin inhibitors are valuable research tools which may have promising therapeutic uses. Here, we foc...

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Detalles Bibliográficos
Autores principales: Hunter, Emma J., Hamaia, Samir W., Gullberg, Donald, Malcor, Jean-Daniel, Farndale, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444087/
https://www.ncbi.nlm.nih.gov/pubmed/34363821
http://dx.doi.org/10.1016/j.taap.2021.115669