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Genome-wide regulation of CpG methylation by ecCEBPα in acute myeloid leukemia
Background: Acute myeloid leukemia (AML) is a hematopoietic malignancy characterized by genetic and epigenetic aberrations that alter the differentiation capacity of myeloid progenitor cells. The transcription factor CEBPα is frequently mutated in AML patients leading to an increase in DNA methylati...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444155/ https://www.ncbi.nlm.nih.gov/pubmed/34557292 http://dx.doi.org/10.12688/f1000research.28146.2 |