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Genome-wide regulation of CpG methylation by ecCEBPα in acute myeloid leukemia

Background: Acute myeloid leukemia (AML) is a hematopoietic malignancy characterized by genetic and epigenetic aberrations that alter the differentiation capacity of myeloid progenitor cells. The transcription factor CEBPα is frequently mutated in AML patients leading to an increase in DNA methylati...

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Detalles Bibliográficos
Autores principales: Ogunleye, Adewale J., Romanova, Ekaterina, Medvedeva, Yulia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444155/
https://www.ncbi.nlm.nih.gov/pubmed/34557292
http://dx.doi.org/10.12688/f1000research.28146.2