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Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

BACKGROUND: Understanding the influence of genetic variants on DNA methylation is fundamental for the interpretation of epigenomic data in the context of disease. There is a need for systematic approaches not only for determining methylation quantitative trait loci (methQTL), but also for discrimina...

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Detalles Bibliográficos
Autores principales: Scherer, Michael, Gasparoni, Gilles, Rahmouni, Souad, Shashkova, Tatiana, Arnoux, Marion, Louis, Edouard, Nostaeva, Arina, Avalos, Diana, Dermitzakis, Emmanouil T., Aulchenko, Yurii S., Lengauer, Thomas, Lyons, Paul A., Georges, Michel, Walter, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444396/
https://www.ncbi.nlm.nih.gov/pubmed/34530905
http://dx.doi.org/10.1186/s13072-021-00415-6