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Androgen receptor regulates the proliferation of myoblasts under appropriate or excessive stretch through IGF-1 receptor mediated p38 and ERK1/2 pathways

BACKGROUND: Androgen receptor (AR) exerts important roles in exercise-induced alterations of muscle mass, in which the proliferation and differentiation of satellite cells or myoblasts are crucial. Our previous study in C2C12 myoblasts demonstrated that 15% (mimic appropriate exercise) and 20% (mimi...

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Detalles Bibliográficos
Autores principales: Fu, Shaoting, Lin, Xiaojing, Yin, Lijun, Wang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444398/
https://www.ncbi.nlm.nih.gov/pubmed/34526063
http://dx.doi.org/10.1186/s12986-021-00610-y