AAV-Mediated Expression of Human VEGF, TNF-α, and IL-6 Induces Retinal Pathology in Mice

PURPOSE: Retinopathies display complex pathologies, including vasculopathies, inflammation, and fibrosis, leading ultimately to visual impairment. However, animal models accurately reflecting these pathologies are lacking. In this study, we evaluate the suitability of using Adeno-associated virus (A...

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Detalles Bibliográficos
Autores principales: Weigelt, Carina M., Fuchs, Holger, Schönberger, Tanja, Stierstorfer, Birgit, Strobel, Benjamin, Lamla, Thorsten, Ciossek, Thomas, Bakker, Remko A., Redemann, Norbert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444492/
https://www.ncbi.nlm.nih.gov/pubmed/34520511
http://dx.doi.org/10.1167/tvst.10.11.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444492/
https://www.ncbi.nlm.nih.gov/pubmed/34520511
http://dx.doi.org/10.1167/tvst.10.11.15

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