Zebrafish toxicological screening could aid Leishmaniosis drug discovery

BACKGROUND: Recently a screen from a library of 1.8 million compounds identified in vitro a potent activity of the 2-aminobenzimidazoles series against Leishmania infantum, the etiological agent responsible by over 20.000 deaths each year. Several analogs were synthesized and in vitro tested through...

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Detalles Bibliográficos
Autores principales: Fukushima, Hirla Costa Silva, Bailone, Ricardo Lacava, Corrêa, Tatiana, Janke, Helena, De Aguiar, Luís Kluwe, Setti, Princia Grejo, Borra, Ricardo Carneiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444568/
https://www.ncbi.nlm.nih.gov/pubmed/34530926
http://dx.doi.org/10.1186/s42826-021-00104-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444568/
https://www.ncbi.nlm.nih.gov/pubmed/34530926
http://dx.doi.org/10.1186/s42826-021-00104-1

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