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Zebrafish toxicological screening could aid Leishmaniosis drug discovery
BACKGROUND: Recently a screen from a library of 1.8 million compounds identified in vitro a potent activity of the 2-aminobenzimidazoles series against Leishmania infantum, the etiological agent responsible by over 20.000 deaths each year. Several analogs were synthesized and in vitro tested through...
Autores principales: | Fukushima, Hirla Costa Silva, Bailone, Ricardo Lacava, Corrêa, Tatiana, Janke, Helena, De Aguiar, Luís Kluwe, Setti, Princia Grejo, Borra, Ricardo Carneiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444568/ https://www.ncbi.nlm.nih.gov/pubmed/34530926 http://dx.doi.org/10.1186/s42826-021-00104-1 |
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