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MD2 contributes to the pathogenesis of perioperative neurocognitive disorder via the regulation of α5GABA(A) receptors in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a long-term postoperative complication in elderly surgical patients. The underlying mechanism of PND is unclear, and no effective therapies are currently available. It is believed that neuroinflammation plays an important role in triggering...

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Detalles Bibliográficos
Autores principales: Zuo, Wenqiang, Zhao, Jianshuai, Zhang, Jinming, Fang, Zongping, Deng, Jiao, Fan, Ze, Guo, Yaru, Han, Jing, Hou, Wugang, Dong, Hailong, Xu, Feifei, Xiong, Lize
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444589/
https://www.ncbi.nlm.nih.gov/pubmed/34530841
http://dx.doi.org/10.1186/s12974-021-02246-4