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The intracellular milieu of Parkinson’s disease patient brain cells modulates alpha-synuclein protein aggregation

Recent studies suggest that brain cell type specific intracellular environments may play important roles in the generation of structurally different protein aggregates that define neurodegenerative diseases. Using human induced pluripotent stem cells (hiPSC) and biochemical and vibrational spectrosc...

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Detalles Bibliográficos
Autores principales: Gustavsson, Nadja, Savchenko, Ekaterina, Klementieva, Oxana, Roybon, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444604/
https://www.ncbi.nlm.nih.gov/pubmed/34530929
http://dx.doi.org/10.1186/s40478-021-01256-w