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Thrombin-activated platelet-rich plasma enhances osteogenic differentiation of human periodontal ligament stem cells by activating SIRT1-mediated autophagy

BACKGROUND: Platelet-rich plasma (PRP) has the potential to be used for bone regeneration. However, its effect on osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) and its effect on cell autophagy of hPDLSCs remain unknown. In this study, we investigated the effects of PR...

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Detalles Bibliográficos
Autores principales: Xu, Yunhe, Wang, Xiaoning, Liu, Wenshu, Lu, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444612/
https://www.ncbi.nlm.nih.gov/pubmed/34526113
http://dx.doi.org/10.1186/s40001-021-00575-x