A case-control study of a combination of single nucleotide polymorphisms and clinical parameters to predict clinically relevant toxicity associated with fluoropyrimidine and platinum-based chemotherapy in gastric cancer

BACKGROUND: Fluoropyrimidine plus platinum chemotherapy remains the standard first line treatment for gastric cancer (GC). Guidelines exist for the clinical interpretation of four DPYD genotypes related to severe fluoropyrimidine toxicity within European populations. However, the frequency of these...

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Detalles Bibliográficos
Autores principales: Cordova-Delgado, Miguel, Bravo, María Loreto, Cumsille, Elisa, Hill, Charlotte N., Muñoz-Medel, Matías, Pinto, Mauricio P., Retamal, Ignacio N., Lavanderos, María A., Miquel, Juan Francisco, Rodriguez-Fernandez, Maria, Liao, Yuwei, Li, Zhiguang, Corvalán, Alejandro H., Armisén, Ricardo, Garrido, Marcelo, Quiñones, Luis A., Owen, Gareth I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444616/
https://www.ncbi.nlm.nih.gov/pubmed/34525956
http://dx.doi.org/10.1186/s12885-021-08745-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444616/
https://www.ncbi.nlm.nih.gov/pubmed/34525956
http://dx.doi.org/10.1186/s12885-021-08745-0

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