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Bioorthogonal dissection of the replicase assembly of hepatitis C virus

Positive-strand RNA viruses such as hepatitis C virus (HCV), flaviviruses, and coronaviruses are medically important. Assembly of replicase on host membranes is a conserved replication strategy and an attractive antiviral target. The mechanisms of replicase assembly are largely unknown, due to the t...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Chen, Shuiye, Yuan, Zhenghong, Yi, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444619/
https://www.ncbi.nlm.nih.gov/pubmed/33798447
http://dx.doi.org/10.1016/j.chembiol.2021.03.006