A Transcriptional Signature of PDGF-DD Activated Natural Killer Cells Predicts More Favorable Prognosis in Low-Grade Glioma

The binding of platelet-derived growth factor D (PDGF-DD) to the NKp44 receptor activates a distinct transcriptional program in primary IL-2 expanded human natural killer (NK) cells. We were interested in knowing if the PDGF-DD-NKp44 pathway of NK cell activation might play a clinically relevant rol...

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Detalles Bibliográficos
Autores principales: Sun, Yuhan, Sedgwick, Alexander James, Palarasah, Yaseelan, Mangiola, Stefano, Barrow, Alexander David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444979/
https://www.ncbi.nlm.nih.gov/pubmed/34539622
http://dx.doi.org/10.3389/fimmu.2021.668391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444979/
https://www.ncbi.nlm.nih.gov/pubmed/34539622
http://dx.doi.org/10.3389/fimmu.2021.668391

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