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A glutamine ‘tug-of-war’: targets to manipulate glutamine metabolism for cancer immunotherapy

Within the tumour microenvironment (TME), there is a cellular ‘tug-of-war’ for glutamine, the most abundant amino acid in the body. This competition is most evident when considering the balance between a successful anti-tumour immune response and the uncontrolled growth of tumour cells that are addi...

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Detalles Bibliográficos
Autores principales: Pallett, Laura J, Dimeloe, Sarah, Sinclair, Linda V, Byrne, Adam J, Schurich, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444990/
https://www.ncbi.nlm.nih.gov/pubmed/34541580
http://dx.doi.org/10.1093/immadv/ltab010