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Effects of Cooling Temperatures via Thermal K2P Channels on Regeneration of High-Frequency Action Potentials at Nodes of Ranvier of Rat Aβ-Afferent Nerves

Temperature-sensitive two-pore domain potassium channels (thermal K2P) are recently shown to cluster at nodes of Ranvier (NRs) and play a key role in action potential (AP) regeneration and conduction on Aβ-afferent nerves. Cooling temperatures affect AP regeneration and conduction on Aβ-afferent ner...

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Detalles Bibliográficos
Autores principales: Kanda, Hirosato, Tonomura, Sotatsu, Gu, Jianguo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445039/
https://www.ncbi.nlm.nih.gov/pubmed/34462308
http://dx.doi.org/10.1523/ENEURO.0308-21.2021