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RIM-Binding Protein 2 Organizes Ca(2+) Channel Topography and Regulates Release Probability and Vesicle Replenishment at a Fast Central Synapse

Rab-interacting molecule (RIM)-binding protein 2 (BP2) is a multidomain protein of the presynaptic active zone (AZ). By binding to RIM, bassoon (Bsn), and voltage-gated Ca(2+) channels (Ca(V)), it is considered to be a central organizer of the topography of Ca(V) and release sites of synaptic vesicl...

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Detalles Bibliográficos
Autores principales: Butola, Tanvi, Alvanos, Theocharis, Hintze, Anika, Koppensteiner, Peter, Kleindienst, David, Shigemoto, Ryuichi, Wichmann, Carolin, Moser, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445062/
https://www.ncbi.nlm.nih.gov/pubmed/34353898
http://dx.doi.org/10.1523/JNEUROSCI.0586-21.2021