Cargando…
Synthesis and delivery of a stable phosphorylated ubiquitin probe to study ubiquitin conjugation in mitophagy
Protein post-translational modifications are involved in essentially all aspects of cellular signaling. Their dynamic nature and the difficulties in installing them using enzymatic approaches limits their direct study in human cells. Reported herein is the first synthesis, delivery and cellular stud...
Autores principales: | Mann, Guy, Satish, Gandhesiri, Sulkshane, Prasad, Mandal, Shaswati, Glickman, Michael H., Brik, Ashraf |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445162/ https://www.ncbi.nlm.nih.gov/pubmed/34528945 http://dx.doi.org/10.1039/d1cc04045f |
Ejemplares similares
-
Enhanced Live‐Cell Delivery of Synthetic Proteins Assisted by Cell‐Penetrating Peptides Fused to DABCYL
por: Mandal, Shaswati, et al.
Publicado: (2021) -
Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1
por: Mann, Guy, et al.
Publicado: (2022) -
Synthesis and Evaluation of Ubiquitin–Dioxetane
Conjugate as a Chemiluminescent Probe for Monitoring Deubiquitinase
Activity
por: Gutkin, Sara, et al.
Publicado: (2021) -
On-Demand
Detachment of Succinimides on Cysteine to
Facilitate (Semi)Synthesis of Challenging Proteins
por: Vamisetti, Ganga B., et al.
Publicado: (2020) -
Probing the cell delivery of synthetic diubiquitin chains
por: Mandal, Shaswati, et al.
Publicado: (2022)