Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolved COVID-19

The aim of this study was to define the breadth and specificity of dominant SARS-CoV-2-specific T cell epitopes using a comprehensive set of 135 overlapping 15-mer peptides covering the SARS-CoV-2 envelope (E), membrane (M) and nucleoprotein (N) in a cohort of 34 individuals with acute (n = 10) and...

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Detalles Bibliográficos
Autores principales: Heide, Janna, Schulte, Sophia, Kohsar, Matin, Brehm, Thomas Theo, Herrmann, Marissa, Karsten, Hendrik, Marget, Matthias, Peine, Sven, Johansson, Alexandra M., Sette, Alessandro, Lütgehetmann, Marc, Kwok, William W., Sidney, John, Schulze zur Wiesch, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445433/
https://www.ncbi.nlm.nih.gov/pubmed/34529740
http://dx.doi.org/10.1371/journal.ppat.1009842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445433/
https://www.ncbi.nlm.nih.gov/pubmed/34529740
http://dx.doi.org/10.1371/journal.ppat.1009842

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