Clinical and molecular characterization of patients fulfilling Chompret criteria for Li-Fraumeni syndrome in Southern Brazil

Li-Fraumeni syndrome (LFS) is an autosomal dominant cancer predisposition syndrome caused by pathogenic germline variants in the TP53 gene, characterized by a predisposition to the development of a broad spectrum of tumors at an early age. The core tumors related to LFS are bone and soft tissue sarc...

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Detalles Bibliográficos
Autores principales: Matzenbacher Bittar, Camila, de Araújo Rocha, Yasminne Marinho, Vieira, Igor Araujo, Rosset, Clévia, Andreis, Tiago Finger, Sartor, Ivaine Tais Sauthier, Artigalás, Osvaldo, Netto, Cristina B. O., Alemar, Barbara, Macedo, Gabriel S., Ashton-Prolla, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445435/
https://www.ncbi.nlm.nih.gov/pubmed/34529667
http://dx.doi.org/10.1371/journal.pone.0251639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445435/
https://www.ncbi.nlm.nih.gov/pubmed/34529667
http://dx.doi.org/10.1371/journal.pone.0251639

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