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GED-0507 attenuates lung fibrosis by counteracting myofibroblast transdifferentiation in vivo and in vitro

The development of more effective, better tolerated drug treatments for progressive pulmonary fibrosis (of which idiopathic pulmonary fibrosis is the most common and severe form) is a research priority. The peroxisome proliferator-activated receptor gamma (PPAR-γ) is a key regulator of inflammation...

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Detalles Bibliográficos
Autores principales: Speca, Silvia, Dubuquoy, Caroline, Rousseaux, Christel, Chavatte, Philippe, Desreumaux, Pierre, Spagnolo, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445472/
https://www.ncbi.nlm.nih.gov/pubmed/34529707
http://dx.doi.org/10.1371/journal.pone.0257281