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GED-0507 attenuates lung fibrosis by counteracting myofibroblast transdifferentiation in vivo and in vitro
The development of more effective, better tolerated drug treatments for progressive pulmonary fibrosis (of which idiopathic pulmonary fibrosis is the most common and severe form) is a research priority. The peroxisome proliferator-activated receptor gamma (PPAR-γ) is a key regulator of inflammation...
Autores principales: | Speca, Silvia, Dubuquoy, Caroline, Rousseaux, Christel, Chavatte, Philippe, Desreumaux, Pierre, Spagnolo, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445472/ https://www.ncbi.nlm.nih.gov/pubmed/34529707 http://dx.doi.org/10.1371/journal.pone.0257281 |
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