Ethacridine inhibits SARS-CoV-2 by inactivating viral particles

The respiratory disease COVID-19 is caused by the coronavirus SARS-CoV-2. Here we report the discovery of ethacridine as a potent drug against SARS-CoV-2 (EC(50) ~ 0.08 μM). Ethacridine was identified via high-throughput screening of an FDA-approved drug library in living cells using a fluorescence...

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Detalles Bibliográficos
Autores principales: Li, Xiaoquan, Lidsky, Peter V., Xiao, Yinghong, Wu, Chien-Ting, Garcia-Knight, Miguel, Yang, Junjiao, Nakayama, Tsuguhisa, Nayak, Jayakar V., Jackson, Peter K., Andino, Raul, Shu, Xiaokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445489/
https://www.ncbi.nlm.nih.gov/pubmed/34478458
http://dx.doi.org/10.1371/journal.ppat.1009898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445489/
https://www.ncbi.nlm.nih.gov/pubmed/34478458
http://dx.doi.org/10.1371/journal.ppat.1009898

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