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A high-frequency single nucleotide polymorphism in the MtrB sensor kinase in clinical strains of Mycobacterium tuberculosis alters its biochemical and physiological properties

The DNA polymorphisms found in clinical strains of Mycobacterium tuberculosis drive altered physiology, virulence, and pathogenesis in them. Although the lineages of these clinical strains can be traced back to common ancestor/s, there exists a plethora of difference between them, compared to those...

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Detalles Bibliográficos
Autores principales: Waturuocha, Uchenna Watson, P. J., Athira, Singh, Krishna Kumar, Malhotra, Vandana, Krishna, M. S., Saini, Deepak Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445491/
https://www.ncbi.nlm.nih.gov/pubmed/34529706
http://dx.doi.org/10.1371/journal.pone.0256664