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Nuclear translocation of the tagged endogenous MAPK MPK-1 denotes a subset of activation events in C. elegans development
The extracellular signal-regulated kinases (ERKs) are mitogen-activated protein kinases (MAPKs) that are utilized downstream of Ras to Raf to MEK signaling to control activation of a wide array of targets. Activation of ERKs is elevated in Ras-driven tumors and RASopathies, and thus is a target for...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Company of Biologists Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445601/ https://www.ncbi.nlm.nih.gov/pubmed/34341823 http://dx.doi.org/10.1242/jcs.258456 |