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Activation of IRE1, PERK and salt-inducible kinases leads to Sec body formation in Drosophila S2 cells

The phase separation of the non-membrane bound Sec bodies occurs in Drosophila S2 cells by coalescence of components of the endoplasmic reticulum (ER) exit sites under the stress of amino acid starvation. Here, we address which signaling pathways cause Sec body formation and find that two pathways a...

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Detalles Bibliográficos
Autores principales: Zhang, Chujun, van Leeuwen, Wessel, Blotenburg, Marloes, Aguilera-Gomez, Angelica, Brussee, Sem, Grond, Rianne, Kampinga, Harm H., Rabouille, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445602/
https://www.ncbi.nlm.nih.gov/pubmed/34350957
http://dx.doi.org/10.1242/jcs.258685