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Lamin regulates the dietary restriction response via the mTOR pathway in Caenorhabditis elegans
Animals subjected to dietary restriction (DR) have reduced body size, low fecundity, slower development, lower fat content and longer life span. We identified lamin as a regulator of multiple dietary restriction phenotypes. Downregulation of lmn-1, the single Caenorhabditis elegans lamin gene, incre...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445603/ https://www.ncbi.nlm.nih.gov/pubmed/34383046 http://dx.doi.org/10.1242/jcs.258428 |