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Lamin regulates the dietary restriction response via the mTOR pathway in Caenorhabditis elegans

Animals subjected to dietary restriction (DR) have reduced body size, low fecundity, slower development, lower fat content and longer life span. We identified lamin as a regulator of multiple dietary restriction phenotypes. Downregulation of lmn-1, the single Caenorhabditis elegans lamin gene, incre...

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Detalles Bibliográficos
Autores principales: Charar, Chayki, Metsuyanim-Cohen, Sally, Bar, Daniel Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445603/
https://www.ncbi.nlm.nih.gov/pubmed/34383046
http://dx.doi.org/10.1242/jcs.258428