Phosphorylated cingulin localises GEF-H1 at tight junctions to protect vascular barriers in blood endothelial cells

Dysfunction of vascular barriers is a critical step in inflammatory diseases. Endothelial tight junctions (TJs) control barrier function, and the cytoplasmic adaptor protein cingulin connects TJs to signalling pathways. However, local events at TJs during inflammation are largely unknown. In this st...

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Detalles Bibliográficos
Autores principales: Holzner, Silvio, Bromberger, Sophie, Wenzina, Judith, Neumüller, Karin, Holper, Tina-Maria, Petzelbauer, Peter, Bauer, Wolfgang, Weber, Benedikt, Schossleitner, Klaudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445606/
https://www.ncbi.nlm.nih.gov/pubmed/34345888
http://dx.doi.org/10.1242/jcs.258557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445606/
https://www.ncbi.nlm.nih.gov/pubmed/34345888
http://dx.doi.org/10.1242/jcs.258557

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