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Phosphorylated cingulin localises GEF-H1 at tight junctions to protect vascular barriers in blood endothelial cells
Dysfunction of vascular barriers is a critical step in inflammatory diseases. Endothelial tight junctions (TJs) control barrier function, and the cytoplasmic adaptor protein cingulin connects TJs to signalling pathways. However, local events at TJs during inflammation are largely unknown. In this st...
Autores principales: | Holzner, Silvio, Bromberger, Sophie, Wenzina, Judith, Neumüller, Karin, Holper, Tina-Maria, Petzelbauer, Peter, Bauer, Wolfgang, Weber, Benedikt, Schossleitner, Klaudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445606/ https://www.ncbi.nlm.nih.gov/pubmed/34345888 http://dx.doi.org/10.1242/jcs.258557 |
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