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Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells

Plasmacytoid dendritic cells (pDCs) constitute a rare type of immune cell with multifaceted functions, but their potential use as a cell-based immunotherapy is challenged by the scarce cell numbers that can be extracted from blood. Here, we systematically investigate culture parameters for generatin...

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Detalles Bibliográficos
Autores principales: Laustsen, Anders, van der Sluis, Renée M, Gris-Oliver, Albert, Hernández, Sabina Sánchez, Cemalovic, Ena, Tang, Hai Q, Pedersen, Lars Henning, Uldbjerg, Niels, Jakobsen, Martin R, Bak, Rasmus O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445615/
https://www.ncbi.nlm.nih.gov/pubmed/34473049
http://dx.doi.org/10.7554/eLife.65528