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Clostridioides difficile infection induces a rapid influx of bile acids into the gut during colonization of the host

Clostridioides difficile is the leading cause of nosocomial intestinal infections in the United States. Ingested C. difficile spores encounter host bile acids and other cues that are necessary for germinating into toxin-producing vegetative cells. While gut microbiota disruption (often by antibiotic...

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Detalles Bibliográficos
Autores principales: Wexler, Aaron G., Guiberson, Emma R., Beavers, William N., Shupe, John A., Washington, M. Kay, Lacy, D. Borden, Caprioli, Richard M., Spraggins, Jeffrey M., Skaar, Eric P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445666/
https://www.ncbi.nlm.nih.gov/pubmed/34496241
http://dx.doi.org/10.1016/j.celrep.2021.109683