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Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection

Certain sulfated glycans, including those from marine sources, can show potential effects against SARS-CoV-2. Here, a new fucosylated chondroitin sulfate (FucCS) from the sea cucumber Pentacta pygmaea (PpFucCS) (MW ∼10–60 kDa) was isolated and structurally characterized by NMR. PpFucCS is composed o...

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Detalles Bibliográficos
Autores principales: Dwivedi, Rohini, Samanta, Priyanka, Sharma, Poonam, Zhang, Fuming, Mishra, Sushil K., Kucheryavy, Pavel, Kim, Seon Beom, Aderibigbe, AyoOluwa O., Linhardt, Robert J., Tandon, Ritesh, Doerksen, Robert J., Pomin, Vitor H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445769/
https://www.ncbi.nlm.nih.gov/pubmed/34537241
http://dx.doi.org/10.1016/j.jbc.2021.101207