Glucose-mediated de novo lipogenesis in photoreceptors drives early diabetic retinopathy

Diabetic retinopathy (DR) is an increasingly frequent cause of blindness across populations; however, the events that initiate pathophysiology of DR remain elusive. Strong preclinical and clinical evidence suggests that abnormalities in retinal lipid metabolism caused by diabetes may account for the...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajagopal, Rithwick, Sylvester, Beau, Zhang, Sheng, Adak, Sangeeta, Wei, Xiaochao, Bowers, Megan, Jessberger, Sebastian, Hsu, Fong-Fu, Semenkovich, Clay F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445899/
https://www.ncbi.nlm.nih.gov/pubmed/34425110
http://dx.doi.org/10.1016/j.jbc.2021.101104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445899/
https://www.ncbi.nlm.nih.gov/pubmed/34425110
http://dx.doi.org/10.1016/j.jbc.2021.101104

Ejemplares similares