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Glucose-mediated de novo lipogenesis in photoreceptors drives early diabetic retinopathy

Diabetic retinopathy (DR) is an increasingly frequent cause of blindness across populations; however, the events that initiate pathophysiology of DR remain elusive. Strong preclinical and clinical evidence suggests that abnormalities in retinal lipid metabolism caused by diabetes may account for the...

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Detalles Bibliográficos
Autores principales: Rajagopal, Rithwick, Sylvester, Beau, Zhang, Sheng, Adak, Sangeeta, Wei, Xiaochao, Bowers, Megan, Jessberger, Sebastian, Hsu, Fong-Fu, Semenkovich, Clay F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445899/
https://www.ncbi.nlm.nih.gov/pubmed/34425110
http://dx.doi.org/10.1016/j.jbc.2021.101104

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