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Glucose-mediated de novo lipogenesis in photoreceptors drives early diabetic retinopathy
Diabetic retinopathy (DR) is an increasingly frequent cause of blindness across populations; however, the events that initiate pathophysiology of DR remain elusive. Strong preclinical and clinical evidence suggests that abnormalities in retinal lipid metabolism caused by diabetes may account for the...
Autores principales: | Rajagopal, Rithwick, Sylvester, Beau, Zhang, Sheng, Adak, Sangeeta, Wei, Xiaochao, Bowers, Megan, Jessberger, Sebastian, Hsu, Fong-Fu, Semenkovich, Clay F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445899/ https://www.ncbi.nlm.nih.gov/pubmed/34425110 http://dx.doi.org/10.1016/j.jbc.2021.101104 |
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