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Receptor binding, immune escape, and protein stability direct the natural selection of SARS-CoV-2 variants

Emergence of new severe acute respiratory syndrome coronavirus 2 variants has raised concerns related to the effectiveness of vaccines and antibody therapeutics developed against the unmutated wildtype virus. Here, we examined the effect of the 12 most commonly occurring mutations in the receptor-bi...

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Detalles Bibliográficos
Autores principales: Upadhyay, Vaibhav, Lucas, Alexandra, Panja, Sudipta, Miyauchi, Ryuki, Mallela, Krishna M.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445900/
https://www.ncbi.nlm.nih.gov/pubmed/34543625
http://dx.doi.org/10.1016/j.jbc.2021.101208