A combination approach of pseudotime analysis and mathematical modeling for understanding drug-resistant mechanisms

Cancer cells acquire drug resistance through the following stages: nonresistant, pre-resistant, and resistant. Although the molecular mechanism of drug resistance is well investigated, the process of drug resistance acquisition remains largely unknown. Here we elucidate the molecular mechanisms unde...

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Detalles Bibliográficos
Autores principales: Magi, Shigeyuki, Ki, Sewon, Ukai, Masao, Domínguez-Hüttinger, Elisa, Naito, Atsuhiko T, Suzuki, Yutaka, Okada, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445918/
https://www.ncbi.nlm.nih.gov/pubmed/34531471
http://dx.doi.org/10.1038/s41598-021-97887-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445918/
https://www.ncbi.nlm.nih.gov/pubmed/34531471
http://dx.doi.org/10.1038/s41598-021-97887-z

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