Cargando…
A combination approach of pseudotime analysis and mathematical modeling for understanding drug-resistant mechanisms
Cancer cells acquire drug resistance through the following stages: nonresistant, pre-resistant, and resistant. Although the molecular mechanism of drug resistance is well investigated, the process of drug resistance acquisition remains largely unknown. Here we elucidate the molecular mechanisms unde...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445918/ https://www.ncbi.nlm.nih.gov/pubmed/34531471 http://dx.doi.org/10.1038/s41598-021-97887-z |