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Persistent hyperammonia and altered concentrations of urea cycle metabolites in a 5-day swine experiment of sepsis

We measured plasma and cerebrospinal fluid (CSF) metabolite concentrations in a 5-day porcine sepsis model of fecal peritonitis. The objectives were: (i) to verify whether the expected pathways that had emerged in previous studies pertain only to the early inflammatory response or persist for the su...

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Detalles Bibliográficos
Autores principales: Ferrario, Manuela, Pastorelli, Roberta, Brunelli, Laura, Liu, Shengchen, Zanella do Amaral Campos, Pedro Paulo, Casoni, Daniela, Z’Graggen, Werner J., Jakob, Stephan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445921/
https://www.ncbi.nlm.nih.gov/pubmed/34531431
http://dx.doi.org/10.1038/s41598-021-97855-7