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Shotgun-based proteomics of extracellular vesicles in Alzheimer’s disease reveals biomarkers involved in immunological and coagulation pathways

Alzheimer’s disease (AD) is the most common form of dementia and without readily available clinical biomarkers. Blood-derived proteins are routinely used for diagnostics; however, comprehensive plasma profiling is challenging due to the dynamic range in protein concentrations. Extracellular vesicles...

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Detalles Bibliográficos
Autores principales: Nielsen, Jonas Ellegaard, Honoré, Bent, Vestergård, Karsten, Maltesen, Raluca Georgiana, Christiansen, Gunna, Bøge, Anna Uhd, Kristensen, Søren Risom, Pedersen, Shona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445922/
https://www.ncbi.nlm.nih.gov/pubmed/34531462
http://dx.doi.org/10.1038/s41598-021-97969-y