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Shotgun-based proteomics of extracellular vesicles in Alzheimer’s disease reveals biomarkers involved in immunological and coagulation pathways
Alzheimer’s disease (AD) is the most common form of dementia and without readily available clinical biomarkers. Blood-derived proteins are routinely used for diagnostics; however, comprehensive plasma profiling is challenging due to the dynamic range in protein concentrations. Extracellular vesicles...
Autores principales: | Nielsen, Jonas Ellegaard, Honoré, Bent, Vestergård, Karsten, Maltesen, Raluca Georgiana, Christiansen, Gunna, Bøge, Anna Uhd, Kristensen, Søren Risom, Pedersen, Shona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445922/ https://www.ncbi.nlm.nih.gov/pubmed/34531462 http://dx.doi.org/10.1038/s41598-021-97969-y |
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