Insulin-like growth factor binding protein-1 regulates HIF-1α degradation to inhibit apoptosis in hypoxic cardiomyocytes

Hypoxia is important in ischemic heart disease. Excessive Insulin-like growth factor binding protein-1 (IGFBP-1) amounts are considered to harm cardiomyocytes in acute myocardial infarction. However, the mechanisms by which IGFBP-1 affects cardiomyocytes remain undefined. The present study demonstra...

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Detalles Bibliográficos
Autores principales: Tang, Xiaoyan, Jiang, Huilin, Lin, Peiyi, Zhang, Zhenhui, Chen, Meiting, Zhang, Yi, Mo, Junrong, Zhu, Yongcheng, Liu, Ningning, Chen, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445926/
https://www.ncbi.nlm.nih.gov/pubmed/34531382
http://dx.doi.org/10.1038/s41420-021-00629-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445926/
https://www.ncbi.nlm.nih.gov/pubmed/34531382
http://dx.doi.org/10.1038/s41420-021-00629-3

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