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Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles
Treatment and prevention of human immunodeficiency virus type one (HIV-1) infection was transformed through widespread use of antiretroviral therapy (ART). However, ART has limitations in requiring life-long daily adherence. Such limitations have led to the creation of long-acting (LA) ART. While nu...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445934/ https://www.ncbi.nlm.nih.gov/pubmed/34531390 http://dx.doi.org/10.1038/s41467-021-25690-5 |