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Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles

Treatment and prevention of human immunodeficiency virus type one (HIV-1) infection was transformed through widespread use of antiretroviral therapy (ART). However, ART has limitations in requiring life-long daily adherence. Such limitations have led to the creation of long-acting (LA) ART. While nu...

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Detalles Bibliográficos
Autores principales:	Cobb, Denise A., Smith, Nathan, Deodhar, Suyash, Bade, Aditya N., Gautam, Nagsen, Shetty, Bhagya Laxmi Dyavar, McMillan, JoEllyn, Alnouti, Yazen, Cohen, Samuel M., Gendelman, Howard E., Edagwa, Benson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445934/ https://www.ncbi.nlm.nih.gov/pubmed/34531390 http://dx.doi.org/10.1038/s41467-021-25690-5

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