TC10 regulates breast cancer invasion and metastasis by controlling membrane type-1 matrix metalloproteinase at invadopodia

During breast cancer metastasis, cancer cell invasion is driven by actin-rich protrusions called invadopodia, which mediate the extracellular matrix degradation required for the success of the invasive cascade. In this study, we demonstrate that TC10, a member of a Cdc42 subfamily of p21 small GTPas...

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Detalles Bibliográficos
Autores principales: Hülsemann, Maren, Sanchez, Colline, Verkhusha, Polina V., Des Marais, Vera, Mao, Serena P. H., Donnelly, Sara K., Segall, Jeffrey E., Hodgson, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445963/
https://www.ncbi.nlm.nih.gov/pubmed/34531530
http://dx.doi.org/10.1038/s42003-021-02583-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445963/
https://www.ncbi.nlm.nih.gov/pubmed/34531530
http://dx.doi.org/10.1038/s42003-021-02583-3

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